Finally we arrive to Via Duomo (Cathedral Street) where is the Cathedral of Naples, seat for the Cardinal and for the Treasure of San Gennaro, the patron saint of the city. Here it happens twice a year the Miracle of San Gennaro, when the Martyr's blood (saved into an ampulla) liquefies, announcing that there will be no calamities for Neapolitans. The actual construction belongs to the Angevin Age too, but here was a paleochristian basilica which had been enclosed into the new cathedral as a lateral chapel. The interiors had been changed during 17th and 18th century, but retain some previous chapels both from Gothic and Renaissance period, causing a much mixed style. The facade has been rebuilt at the end of 19th century following the neoclassical style, but the portals belongs to the 15th century and are decorated with statues of the 14th century.

Many other monuments, churches and works of art are located in the old centre of Naples. Beyond the ones already mentioned, we suggest also: The Sansevero Chapel, with the statue of the Veiled Christ; the Brancaccio Chapel, with the low relief by Donatello; the Church and Monastery of San Lorenzo Maggiore, with the underlying excavations of the Greek and Roman city; the conventual complex of Girolamini, with the paintings by Luca Giordano, Pietro da Cortona and Guido Reni (among the maximum artists of Italian Baroque).